Social impact assessment of investment activities in the China–Pakistan economic corridor

In order to analyze potential social risks, and achieve smooth implementation of investment activities in the China–Pakistan economic corridor (CPEC), we attempt to establish social impact and risk indicators. Both the impacts on the projects and the impacts of the projects are used to develop risk indicators in accordance with the literature review, reality and international standard principles. Using an analytic hierarchy process (AHP) and average value to analyze questionnaires of both Chinese and Pakistani respondents, we identify the importance of various risk indicators. The primary social risks of the western high mountain region include tribal obstacles and religious extremism. The social risks to the southeast coastal plains include preserving the historical and cultural heritage of the area and international protection of national parks. The social risks in north Kashmir include disputes, extremist threats, religious and cultural differences, and the protection of natural reserves. The social risks of the Xinjiang region primarily involve social issues faced by ethnic minorities and environmental pressures.     

基于二元水循环的水量-水质-水效联合调控模型开发与应用

为将我国最严格水资源管理制度的实践与二元水循环理论相结合，提高“三条红线”控制指标的科学性与合理性，本文以SWAT模型为基础，通过改进子流域划分方法、添加经济社会模块和人工用水模块，对其人工侧支循环模拟进行了系统的完善，开发了基于SWAT的水量-水质-水效联合调控模型SWAT_WAQER。以广西南流江流域为例，从国民经济用水量、河道径流与水质等方面对模型进行校验，并在此基础上划分了2030年“三条红线”控制指标。结果表明：该模型性能良好，能够用于不同节水情景下的国民经济用水量、污染物排放量、水功能区水质达标结果分析，可以作为科学制定“三条红线”控制指标的有力支撑工具。     

‘Breaking’ news: uncovering sense-breaking patterns in social media crisis communication during the 2017 Manchester bombing

ABSTRACT

Individuals, (media-) organisations, and crisis responders who are involved in ad hoc crisis communication steadily deploy social media to contribute to collective sense-making as an endeavour to create meaning in highly uncertain situations. Exerting sense-giving in order to shape others’ conceptions is causally preceded by an initial breakup of existing understanding. This study aims to explore patterns of sense-breaking in social media crisis communication and its impact on collective sense-making and sense-giving. To this end, we conducted a case study of the Manchester bombing in 2017, including a social network analysis of 708,147 Twitter postings and a content analysis of 2006 original tweets. We found individual role types to be initiators of sense-breaking in early crisis stages when uncertainty is at its height. Exerting successive sense-giving becomes more challenging if the collective sense-making has progressed along with the sequence of events. This understanding aims to encourage emergency management organisations to move their sense-giving actions closer to the point in time when sense-breaking occurs.     

吐哈盆地克尔碱凹陷煤层煤质特征与成煤环境

为了揭示吐哈盆地克尔碱凹陷不同矿区煤质形成条件，探讨该区煤质与成煤环境的关系，基于对主采煤层样品工业分析、有害组分及灰成分指标等数据分析，在对克尔碱凹陷地层分布、含煤岩系特征等基本地质条件分析的基础上，运用煤地质学、煤岩学、煤化学等理论和方法，系统总结凹陷内各矿区煤层赋存特征、煤质特征，探讨区内煤岩煤质与成煤环境的关系。结果表明：研究区自西向东划分6个主要矿区,区内煤层主要发育于中侏罗统西山窑组（J2x）和下侏罗统八道湾组（J1b）地层之中。研究区煤质呈低灰、低硫、高挥发分特征，煤灰成分以SiO2、Al2O3为主。综合分析表明，研究区中-下侏罗统主要煤层形成于湖泊-河流三角洲淡水沉积环境，具陆相成煤特征，成煤环境温暖潮湿。     

Exchanging social support on online teacher groups: Relation to teacher self-efficacy

The present study explored the relation between exchanging social support on online teacher groups and teacher self-efficacy. An online survey was conducted inside a massive Facebook teacher group, and 584 elementary school teachers provided information regarding Facebook use, self-efficacy for creative teaching, and the extent to which they provided and received support on the online teacher group. Results showed that teacher self-efficacy varied as a function of years of teaching experience, length of group membership, and the extent to which teachers provided and received social support on the online teacher group. Furthermore, the providing of online support predicted teacher self-efficacy after taking into account the effects of teaching experience and group membership. The findings are discussed in terms of the features and importance of social support exchange on online teacher support groups.     

Improving the risk management of Type 2 diabetes mellitus in China from the perspective of social relationships

In China, Type 2 diabetes mellitus (T2DM) is increasingly affecting people's health. Although many risk factors related to T2DM have been researched, the association between social relationships and risk management of T2DM in China has not been fully researched. Therefore, we obtained 2,969 valid cases from the National Chinese Medicine Clinical Research Base-Key Disease of Diabetes Mellitus Study to evaluate the role of social relationships in the risk management of T2DM. We first establish an indicators system of social relationship factors and then propose a comprehensive method that integrates subjective (analytical network process) and objective (entropy weight method) evaluations to rank the importance of the 17 social relationship factors that were the most important and commonly used. The results suggest that different social relationship factors have different effects on the risk management of T2DM. Patients and health workers should pay more attention to the high-benefit factors and thus improve the efficiency of the risk management of T2DM. These findings provided theoretical support for patients and health workers by developing the positive effects of social relationships in improving the risk management of T2DM to the fullest degree.     

40万t/年转炉钢渣蒸汽陈化处理生产线

介绍了针对国内某炼钢厂专门设计的40万t/年转炉钢渣蒸汽陈化处理生产线主要参数及工艺流程,对该生产线中的钢渣倾翻车、钢渣冷却搅碎车、转运车、蒸汽陈化釜等主要设备特点进行了阐述,同时对该生产线应用的冷却水量研究、搅碎辊轨迹优化等关键技术作了进一步的探讨。     

Histological Evaluation and Gene Expression Profiling of Autophagy-Related Genes for Cartilage of Young and Senescent Rats

Autophagy is a cellular mechanism that protects cells from stress by digesting non-functional cellular components. In the cartilage, chondrocytes depend on autophagy as a principal mechanism to maintain cellular homeostasis. This protective role diminishes prior to the structural damage that normally occurs during aging. Considering that aging is the main risk factor for osteoarthritis, evaluating the expression of genes associated with autophagy in senescent cartilage might allow for the identification of potential therapeutic targets for treatment. Thus, we studied two groups of young and senescent rats. A histological analysis of cartilage and gene expression quantification for autophagy-related genes were performed. In aged cartilage, morphological changes were observed, such as an increase in cartilage degeneration as measured by the modified Mankin score, a decrease in the number of chondrocytes and collagen II (Col2a1), and an increase in matrix metalloproteinase 13 (Mmp13). Moreover, 84 genes associated with autophagy were evaluated by a PCR array analysis, and 15 of them were found to be significantly decreased with aging. Furthermore, an in silico analysis based on by two different bioinformatics software tools revealed that several processes including cellular homeostasis, autophagosome assembly, and aging—as well as several biological pathways such as autophagy, insulin-like growth factor 1 (IGF-1) signaling, PI3K (phosphoinositide 3-kinase)/AKT (serine/threonine kinase) signaling, and mammalian target of rapamycin (mTOR) signaling—were enriched. In conclusion, the analysis identified some potential targets for osteoarthritis treatment that would allow for the development of new therapeutic strategies for this chronic disease.     

Alterations in the Genomic Distribution of 5hmC in In Vivo Aged Human Skin Fibroblasts

5-Hydroxymethylcytosine (5hmC) is a functionally active epigenetic modification. We analyzed whether changes in DNA 5-hydroxymethylation are an element of age-related epigenetic drift. We tested primary fibroblast cultures originating from individuals aged 22–35 years and 74–94 years. Global quantities of methylation-related DNA modifications were estimated by the dot blot and colorimetric methods. Regions of the genome differentially hydroxymethylated with age (DHMRs) were identified by hMeDIP-seq and the MEDIPS and DiffBind algorithms. Global levels of DNA modifications were not associated with age. We identified numerous DHMRs that were enriched within introns and intergenic regions and most commonly associated with the H3K4me1 histone mark, promoter-flanking regions, and CCCTC-binding factor (CTCF) binding sites. However, only seven DHMRs were identified by both algorithms and all of their settings. Among them, hypo-hydroxymethylated DHMR in the intron of Rab Escort Protein 1 (CHM) coexisted with increased expression in old cells, while increased 5-hydroxymethylation in the bodies of Arginine and Serine Rich Protein 1 (RSRP1) and Mitochondrial Poly(A) Polymerase (MTPAP) did not change their expression. These age-related differences were not associated with changes in the expression of any of the ten-eleven translocation (TET) enzymes or their activity. In conclusion, the distribution of 5hmC in DNA of in vivo aged human fibroblasts underwent age-associated modifications. The identified DHMRs are, likely, marker changes.     

Evaluation of small-scale combustion of an insensitive high explosive formulation containing 3-nitro-1,2,4-triazol-5-one (NTO), 2,4-dinitroanisole (DNAN), and 1,3,5-trinitroperhydro-1,3,5-triazine (RDX)

ABSTRACT

Energetic materials are often disposed by open-burning or open-detonation as it is a cost-effective and efficient means of destroying explosive material, and often minimizes the need to transport hazardous explosives to treatment facilities. This practice is often scrutinized for the negative environmental impact of the odorous and unsightly toxic gaseous emissions as well as the resulting deposition residues, which often contain unburned energetic materials. With the increasing use of Insensitive High Explosive compositions in munitions, it is essential that the potential environmental impact of their disposal is assessed before their extensive use to prevent the kind of contamination incidents experienced with legacy explosives. Therefore, the aim of this work was to develop a controlled laboratory experiment to identify the gaseous emissions and the energetic material residues that are generated through the combustion of the IHE components 3-nitro-1,2,4-triazol-5-one (NTO), 2,4-dinitroanisole (DNAN), and 1,3,5-trinitroperhydro-1,3,5-triazine (RDX). A sealed vial containing small (mg) quantities of energetic material was heated until the energetic material combusted. Gas chromatography/mass spectrometry (GCMS) was used to calculate the oxygen consumption and to identify the gases that were generated. The solid residues were analyzed by high-performance liquid chromatography (HPLC) to quantify unburned energetic material. Results showed that DNAN was the most resistant to burning, thus leaving significant quantities of unreacted starting material in the vial. An interesting observation for the IHE formulation was that DNAN also inhibited the combustion of NTO and RDX. The gases emitted during the open burning of IHE components and mixtures included CO, CO₂, and N₂O as expected, but the proportions differed when the components and mixture were compared, reflecting the influence of DNAN on the burning behavior. From our data, we concluded that open-burning DNAN-based formulations is an environmentally unfavorable waste-management practice for the disposal of IHEs mainly due to generation of solid residues as well as unburnt DNAN.